One of the main reasons I accept the fact of evolution is that in my professional life as a doctor, the evidence for it is overwhelming. Comparative genomics declares the truth of human-ape common ancestry. Population genetics confirms that it is impossible for the entire human race to descend exclusively from two people living 6000 years ago. The human genome, far from being an elegant model of design precision is a sub-optimal structure that causes disease and which bears the hallmarks of its evolutionary origin. Furthermore, evolutionary principles are of increasing utility to medicine, from casting light on the frankly bizarre and sub-optimal nature of human anatomy and developmental biology to the emerging science of evolutionary medicine. I can no more deny the fact of evolution than I can deny the atomic structure of matter or any other uncontroversial fact of nature.
It's not just medicine in which evolutionary principles are of considerable utility. Agriculture is another area in which recognising the fact of evolution pays considerable real-world dividends, as Andrew Hendry et al pointed out in a 2011 review article in the journal Evolutionary Applications:
Evolutionary principles are now routinely incorporated into medicine and agriculture. Examples include the design of treatments that slow the evolution of resistance by weeds, pests, and pathogens, and the design of breeding programs that maximize crop yield or quality. Evolutionary principles are also increasingly incorporated into conservation biology, natural resource management, and environmental science. Examples include the protection of small and isolated populations from inbreeding depression, the identification of key traits involved in adaptation to climate change, the design of harvesting regimes that minimize unwanted life-history evolution, and the setting of conservation priorities based on populations, species, or communities that harbor the greatest evolutionary diversity and potential. The adoption of evolutionary principles has proceeded somewhat independently in these different fields, even though the underlying fundamental concepts are the same. We explore these fundamental concepts under four main themes: variation, selection, connectivity, and eco-evolutionary dynamics. Within each theme, we present several key evolutionary principles and illustrate their use in addressing applied problems. We hope that the resulting primer of evolutionary concepts and their practical utility helps to advance a unified multidisciplinary field of applied evolutionary biology.
That of course puts the evolution denialists in our community - particularly those who are laypeople with zero professional qualifications in evolutionary biology who do not understand the subject well enough to comment on it, let alone offer an authoritative opinion on it - in the curious position of making outlandish claims about evolution being 'science falsely so-called' which are flatly refuted by the fact that this 'science so-called' has real-world, tangible applications. Ours is an age in which the ability to critically evaluate claims made in lectures is as simple as checking mainstream scientific sites via smart phones and other devices, a fact which should remind evolution denialists in our community to exercise caution and intelligence before making claims that can readily be debunked. Credibility once lost is never regained, even if frantic attempts to substitute intimidation and misrepresentation for factuality are employed.