Intelligent design advocates claim that biochemical systems such as the vertebrate blood clotting cascade are too complex to have evolved. Such claims betray considerable ignorance of the fact that mainstream scientific explanations for the evolution of the vertebrate blood clotting pathway exist. Russell Doolittle, the respected biochemist who literally wrote the book on the subject provides an accessible overview of the subject, and in the process comprehensively demolishes the ID claim. For those who have ears to hear, mainstream science sounds the death-knell for the pseudoscience of intelligent design, and shows that there is simply no such thing as 'irreducible complexity'.